Objectives: To compare the efficacy of newer drug cabergoline with estrogen-androgen combination in lactation inhibition and suppression.
Methods: In a tertiary care teaching hospital, 196 postpartum women in need of inhibition or suppression of lactation were randomly divided into Group A (100 women who were given tablet cabergoline orally) and Group B (96 women who were given estrogen-androgen combination intramuscularly). Both groups were followed till complete cessation of milk expulsion. Number of days and extra doses of drug required were recorded and statistically analyzed on SPSS version 10 of windows 2000.
Results: The mean number of days required was significantly less (0.73+0.963) in Group A, (p value=0.001). Extra doses of drug were needed less often in Group A (p value=0.017).
Conclusion: Cabergoline is more effective drug for prevention and suppression of lactation with added advantage of oral route and easy dosage schedule.
